TY - JOUR
T1 - Emetine and cephaeline content in plants of psychotria ipecacuanha in costa rica
AU - Rosales-López, Catalina
AU - Muñoz-Arrieta, Rodrigo
AU - Abdelnour-Esquivel, Ana
N1 - Publisher Copyright:
© 2020, Universidad Nacional de Colombia. All rights reserved.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - The objective of this study was to identify the emetic metabolites in different parts of the P. ipecacuanha, a plant with emetic properties. Partial phytochemical analysis was performed to determine the presence of emetine and cephaeline in leaves, stems and roots. Both alkaloids were detected in the three plant parts analyzed. Highest alkaloid content was found in roots (8.55 mg/g), followed by stems (4.05 mg/g), and the lowest was found in leaves (2.4 mg/g). The cephaeline content (8.35 mg/g) was higher than that of emetine (6.65 mg/g) in all the three organs analyzed. Toxicity analysis of the crude extract showed a LD50 of 500 mg/kg.
AB - The objective of this study was to identify the emetic metabolites in different parts of the P. ipecacuanha, a plant with emetic properties. Partial phytochemical analysis was performed to determine the presence of emetine and cephaeline in leaves, stems and roots. Both alkaloids were detected in the three plant parts analyzed. Highest alkaloid content was found in roots (8.55 mg/g), followed by stems (4.05 mg/g), and the lowest was found in leaves (2.4 mg/g). The cephaeline content (8.35 mg/g) was higher than that of emetine (6.65 mg/g) in all the three organs analyzed. Toxicity analysis of the crude extract showed a LD50 of 500 mg/kg.
KW - Chemical analysis
KW - Emetic
KW - HPLC, TLC
KW - Ipecac
KW - Second metabolites
UR - http://www.scopus.com/inward/record.url?scp=85087966874&partnerID=8YFLogxK
U2 - 10.15446/rev.colomb.quim.v49n2.78347
DO - 10.15446/rev.colomb.quim.v49n2.78347
M3 - Artículo
AN - SCOPUS:85087966874
SN - 0120-2804
VL - 49
SP - 18
EP - 22
JO - Revista Colombiana de Quimica
JF - Revista Colombiana de Quimica
IS - 2
ER -