PEDOT:PSS: A Conductive and Flexible Polymer for Sensor Integration in Organ-on-Chip Platforms

W. F. Quirós-Solano, N. Gaio, C. Silvestri, G. Pandraud, P. M. Sarro

Research output: Contribution to journalConference articlepeer-review

24 Scopus citations

Abstract

Sensing and stimulating microstructures are necessary to develop more specialized and highly accurate Organ-on-Chip (OOC) platforms. In this paper, we present the integration of a conductive polymer, poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), on a stretchable membrane, core element of an Heart-on-Chip. The electrical conductivity along with its biocompatibility, high transparency (≈88%) and mechanical elasticity (≈1.2 GPa) make this material a candidate to develop novel microstructures for electrical monitoring and stimulation of cells in flexible-substrate based OOCs. Microstructures with different shapes and geometries of PEDOT:PSS embedded in a 9 μm-thick Polydimethylsiloxane (PDMS) membrane are developed following a wafer-level fabrication approach. PEDOT:PSS layers between 120 nm and 300 nm are obtained by varying the deposition conditions. The layers are successfully patterned and microstructures with lateral dimensions down to 2 μm. The obtained results indicate that this polymer is a suitable material for microfabrication of sensing and stimulating elements in OOC platforms.

Original languageEnglish
Pages (from-to)1184-1187
Number of pages4
JournalProcedia Engineering
Volume168
DOIs
StatePublished - 2016
Event30th Eurosensors Conference, Eurosensors 2016 - Budapest, Hungary
Duration: 4 Sep 20167 Sep 2016

Keywords

  • Cell
  • Heart-on-Chip
  • Membrane
  • Microenvironment
  • Organ-on-Chip
  • PDMS
  • Sensing

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